Bone analysis of the femurs after OVX. A-C, pQCT data of BMD of sham and ovariectomized mouse femurs. A, total BMD. B, cortical BMD. C, trabecular BMD. D–F, μCT measurement of the femur trabeculae. D, BV/TV. E, Tb.Th. F, Tb.N. Results are represented as the mean ± S.E. of 4 or 5 analysis for WT or KO mice, respectively. * or ** for p < 0.05 or p < 0.01 compared with the sham operation, respectively.