Figure 1.

Effect of metyrapone on maternal weight gain. Maternal weight gain was measured in grams from day 13 until day 21. Rats were treated with a control 20% diet or a 6% isocaloric low protein diet with or without the glucocorticoid synthesis inhibitor metyrapone. Metyrapone groups gained more weight than the group eating a comparable protein diet without metyrapone. *P < 0.001 vs. all groups. ⁺P ≤ 0.005 vs. 20% protein and 20% protein metyrapone. Pro, protein.