Table 4.

Hazard Ratios for pathways between known resistance locations

Hazard ratios between known resistance locations
Pathway	Hazard	Confidence Bounds
41 → 108	7.54	(2.2, 25.8)
67 → 70	3.52	(2.08, 5.98)
67 → 190	3.19	(1.41, 7.21)
67 → 219	2.97	(1.72, 5.14)
70 → 210*	0.33	(0.15, 0.75)
70 → 219	2.68	(1.6, 4.47)
74 → 100	12.92	(3.48, 47.95)
77 → 103	7.76	(2.6, 23.16)
115 → 106	17.51	(1.26, 243.88)
116 → 62	27.81	(8.73, 88.58)
151 → 116	237.67	(34.71, 1627.63)
181 → 65	3.28	(1.22, 8.81)
184 → 181†	1.77	(1.07, 2.92)
184 → 210	0.27	(0.17, 0.42)
190 → 184	1.84	(1.15, 2.95)
210 → 70	0.09	(0.03, 0.23)
215 → 41	3.23	(2.15, 4.85)
215 → 65	0.06	(0.01, 0.28)

Estimated hazard ratios and 95% confidence bounds for all pathways between known resistance locations with p < 0.01. Two additional pathways, which were remarked on in the text, are also included. Estimation was done using the survival [24] package of the R software environment [22].

*p = 0.011 ^†p= 0.019