Table 3. Number of DNA strand breaks inhibited by resveratrol or/and BTP against DMBA and TPA- induced DNA alkylation damage.
| Groups | Treatment | Number of DNA strand breaks (n) |
| II | DMBA+TPA | 1.50±0.17 |
| IV | DMBA+TPA+resveratrol | 0.81±0.18a (45.79%) |
| V | DMBA+TPA+BTP | 0.90±0.19a (40.52%) |
| VI | DMBA+TPA+resveratrol+BTP | 0.60±0.14b (60.53%) |
Data are expressed as mean ± SD of five animals. ‘n’ represents number of strand breaks of duplex DNA over untreated control group.
a
significant prevention over DMBA and TPA- induced DNA strand breaks (p<0.01).
b
significant prevention over BTP and Res alone treated groups IV and V(p<0.01).
Values in parenthesis represents the percentage prevention offered by resveratrol or/and BTP against DMBA and TPA- induced DNA strand breaks.