Table 3.
Comparison of wavelength selection for PLS and SVR calibration models in human subjects.
| PLS |
SVR |
|||
|---|---|---|---|---|
| 300 | 900 | 300 | 900 | |
| spectral | spectral | spectral | spectral | |
| points | points | points | points | |
| RMSEP | 18.6 | 16.9 | 15.1 | 11.3 |
| R2 | 0.87 | 0.89 | 0.92 | 0.95 |
| Percentage of points satisfying ISO criteria | 86.66 | 89.17 | 88.33 | 94.17 |
a
We report the enhanced robustness obtained for quantitative biological Raman spectroscopy by employing feature selection-based nonlinear support vector calibration. Importantly, we demonstrate the transferability of spectral subsets from one human subject to another for transcutaneous blood glucose measurements.