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. 2011 Aug 1;11:207. doi: 10.1186/1471-2334-11-207

Table 1.

Parameters used in simulations

Parameter Description Value/Range Source
p probability of being confirmed 0.2 or 0.65 low probability [84,86], high probability [55]

α relative infectiousness of unconfirmed class 0.5 based on reduced viral shedding [55-57]

ta start of vaccination campaign (day) 20, 50, or 80 set to occur 10, 40, or 70 days after t0

tb end of vaccination campaign (day) Variable depends on campaign start and duration

td depletion of vaccine stockpile (day) Variable depends on stockpile size; see Inline graphic

t0 time of initiating pulse (day) 10 arbitrary

x0 Amplitude of initiating pulse (individuals) 1 previous epidemiological model [62]

a width of initiating pulse (days) 1 previous epidemiological model [62]

b mean probability of infection per contact 0.476 or 0.346 adjusted as function of p so R0* = 2.0; see sea-sonal/pandemic R0 values [1,87]

c rate of recovery (1/days) 1/7 based on symptoms, viral shedding, cytokine levels [55,58,59]

N total population size 108 e.g. Mexico, Phillipines [69,70]

Inline graphic vaccine stockpile size 30 * 106 based on 30% coverage; see vaccine production/distribution data [21,60,61]

Inline graphic maximum number of vaccines per day 105 - 107 based on vaccination clinic modeling and clinic data [25-30]

k proportion of eligible vaccinated per day 0.001 - 0.1 (0.1-10%) see models using proportions in this range [17,36,38,44]

δ infection-related death rate (1/days) 10-6 based on U.S. viral surveillance data [88]

*R0: Basic reproduction number, defined as the number of secondary infections occurring due to introduction of 1 infected individual into a susceptible population (for review see [89])