Table 3.
Cyclin group | Cyclin sub- families |
Pearson correlation; GLS (R:stats [74]) fitting of n = α + βx |
Webster et al. [101]statistics*; GLS (R:stats [74]) fitting of n = βxδ |
Venditti et al. [100]and Pagel et al. [99]statistics** | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
R2 | α ± SE | p-value | β ± SE | p-value | δ ± SE | p-value | β ± SE | p-value | 1/δ < 1 & signi-ficant β | Signi-ficant β | ||
Inv cyclins: coelenterates, echinodermates, insects. | A | 0.7163 | 0.18 ± 0.12 | 0.1807 | 0.85 ± 0.18 | 0.001 | 1.40 ± 0.36 | 0.0036 | 0.18 ± 0.07 | 0.0308 | 0 | 1 |
B | 0.8456 | 0.44 ± 0.14 | 0.0152 | 0.92 ± 0.15 | 0.0004 | 1.58 ± 0.28 | 0.0007 | 0.31 ± 0.08 | 0.0054 | 0 | 0 | |
B3 | 0.8496 | 0.92 ± 0.10 | 0.000008 | 0.92 ± 0.13 | 0.00006 | 2.53 ± 0.38 | 0.0001 | 0.68 ± 0.09 | 0.00004 | 0 | 1 | |
D | 0.4892 | 0.36 ± 0.21 | 0.1297 | 0.70 ± 0.25 | 0.0244 | 1.79 ± 0.79 | 0.0537 | 0.35 ± 0.16 | 0.0647 | 0 | 0 | |
E | 0.3226 | 0.36 ± 0.24 | 0.1723 | 0.57 ± 0.29 | 0.0868 | 2.11 ± 1.23 | 0.1245 | 0.36 ± 0.18 | 0.0891 | 0 | 0 | |
Inv cyclins: echinodermates, insects. | A | 0.5561 | 0.15 ± 0.22 | 0.5080 | 0.75 ± 0.25 | 0.0211 | 1.28 ± 0.51 | 0.0392 | 0.15 ± 0.10 | 0.1810 | 0 | 0 |
B | 0.6706 | 0.47 ± 0.28 | 0.1608 | 0.82 ± 0.26 | 0.0242 | 1.57 ± 0.53 | 0.0311 | 0.31 ± 0.16 | 0.1040 | 0 | 0 | |
B3 | 0.7240 | 0.97 ± 0.17 | 0.0007 | 0.85 ± 0.20 | 0.0036 | 2.54 ± 0.65 | 0.0057 | 0.68 ± 0.16 | 0.0036 | 0 | 1 | |
D | 0.2700 | 0.50 ± 0.34 | 0.1939 | 0.52 ± 0.35 | 0.1869 | 2.30 ± 1.70 | 0.2240 | 0.47 ± 0.27 | 0.1380 | 0 | 0 | |
E | 0.0819 | 0.53 ± 0.48 | 0.3067 | 0.29 ± 0.39 | 0.4920 | 2.79 ± 3.86 | 0.4970 | 0.45 ± 0.43 | 0.3350 | 0 | 0 | |
Ver cyclins: lower and higher chordates | A1 | 0.0380 | 0.58 ± 0.25 | 0.0471 | 0.19 ± 0.33 | 0.5657 | 3.73 ± 1.00 | 0.0020 | 0.32 ± 0.05 | 0.00003 | 0 | 0 |
A2 | 0.3713 | 0.38 ± 0.08 | 0.0014 | 0.61 ± 0.26 | 0.0466 | 3.83 ± 1.19 | 0.0063 | 0.37 ± 0.07 | 0.0002 | 0 | 1 | |
B1 | 0.1989 | 1.00 ± 0.06 | 0 | 0.45 ± 0.30 | 01691 | 11.9 ± 6.36 | 0.0877 | 0.89 ± 0.10 | 0 | 0 | 0 | |
B2 | 0.8209 | 0.86 ± 0.04 | 0 | 0.91 ± 0.14 | 0.0001 | 5.34 ± 0.60 | 0 | 0.69 ± 0.04 | 0 | 0 | 1 | |
B3 | 0.6674 | 0.62 ± 0.25 | 0.0372 | 0.82 ± 0.20 | 0.0039 | 1.70 ± 0.47 | 0.0064 | 0.43 ± 0.16 | 0.0257 | 1 | 1 | |
D1 | 0.9021 | 0.19 ± 0.05 | 0.0046 | 0.95 ± 0.10 | 0.000008 | 1.70 ± 0.17 | 0 | 0.22 ± 0.03 | 0 | 0 | 1 | |
D2 | 0.5802 | 0.24 ± 0.04 | 0.0002 | 0.76 ± 0.22 | 0.0064 | 3.33 ± 0.66 | 0.0003 | 0.21 ± 0.03 | 0 | 0 | 0 | |
D3 | 0.6270 | 0.24 ± 0.11 | 0.0614 | 0.79 ± 0.23 | 0.0110 | 2.02 ± 0.65 | 0.0168 | 0.23 ± 0.07 | 0.0162 | 0 | 0 | |
E1 | 0.4468 | 0.45 ± 0.14 | 0.0102 | 0.67 ± 0.25 | 0.0245 | 2.95 ± 0.86 | 0.0042 | 0.40 ± 0.09 | 0.0006 | 0 | 0 | |
E2 | 0.7841 | 0.22 ± 0.13 | 0.1125 | 0.89 ± 0.15 | 0.0003 | 2.79 ± 0.79 | 0.0031 | 0.43 ± 0.10 | 0.0007 | 0 | 0 | |
Ver cyclins: coelenterates, lower and higher chordates | A1 | 0.1317 | 0.50 ± 0.12 | 0.0008 | 0.36 ± 0.23 | 0.1267 | 3.99 ± 2.25 | 0.0940 | 0.39 ± 0.13 | 0.0082 | 0 | 1 |
A2 | 0.6144 | 0.38 ± 0.4 | 0 | 0.78 ± 0.15 | 0.00007 | 3.56 ± 0.68 | 0.00006 | 0.31 ± 0.04 | 0 | 0 | 0 | |
B1 | 0.4895 | 0.93 ± 0.04 | 0 | 0.70 ± 0.20 | 0.0037 | 7.88 ± 1.98 | 0.0016 | 0.79 ± 0.06 | 0 | 0 | 0 | |
B2 | 0.8826 | 0.87 ± 0.02 | 0 | 0.94 ± 0.09 | 0 | 5.45 ± 0.47 | 0 | 0.70 ± 0.03 | 0 | 0 | 1 | |
B3 | 0.7127 | 0.80 ± 0.15 | 0.0004 | 0.84 ± 0.17 | 0.0006 | 2.23 ± 0.5 | 0.0012 | 0.59 ± 0.13 | 0.0011 | 0 | 1 | |
D1 | 0.7631 | 0.32 ± 0.05 | 0.00005 | 0.87 ± 0.13 | 0.00002 | 2.35 ± 0.42 | 0.00007 | 0.30 ± 0.04 | 0.00001 | 0 | 1 | |
D2 | 0.0208 | 0.38 ± 0.05 | 0.000003 | 0.14 ± 0.26 | 0.5943 | 41.0 ± 138 | 0.771 | 0.39 ± 0.06 | 0 | 0 | 0 | |
D3 | 0.4942 | 0.36 ± 0.08 | 0.0019 | 0.70 ± 0.24 | 0.0158 | 3.15 ± 1.11 | 0.0197 | 0.34 ± 0.07 | 0.0011 | 0 | 0 | |
E1 | 0.6326 | 0.44 ± 0.07 | 0.00002 | 0.80 ± 0.15 | 0.00008 | 2.70 ± 0.51 | 0.00008 | 0.37 ± 0.06 | 0 | 0 | 0 | |
E2 | 0.6198 | 0.46 ± 0.09 | 0.00007 | 0.79 ± 0.15 | 0.00006 | 2.46 ± 0.46 | 0.00005 | 0.38 ± 0.07 | 0.00002 | 0 | 0 | |
Fungal cyclins | CLB3-4 | 0.6515 | 0.69 ± 0.24 | 0.0229 | 0.81 ± 0.22 | 0.0085 | 1.95 ± 0.59 | 0.0132 | 0.53 ± 0.18 | 0.0190 | 1 | 1 |
CDC13 | 0.1984 | 1.01 ± 0.13 | 0.00003 | 0.45 ± 0.30 | 0.1698 | 6.41 ± 4.40 | 0.1784 | 0.84 ± 0.21 | 0.0032 | 0 | 0 |
* Significant δ ≤ 1 and β > 0, evidence for punctual evolution.
** Significant β, node density artefact present; δ < 1 and significant β, evidence for punctual evolution.
Cyclin groups under impact of punctual evolution are in bold.