Table 4.
Skewness of atypical replacement samples to positions in the protein globule | ||||||
---|---|---|---|---|---|---|
Interior positions in globule (p)* | Surface positions in globule (p)* | |||||
Cyclin families | DSSP ASA values | 10 ASA classes |
3 ASA classes |
DSSP ASA values | 10 ASA classes |
3 ASA classes |
A animal | 0.9966 | 0.9957 | 0.9906 | 0.0034 | 0.0043 | 0.0095 |
B animal | 0.9570 | 0.9772 | 0.9678 | 0.0432 | 0.0230 | 0.0324 |
B fungal | 0.6029 | 0.7785 | 0.7500 | 0.3983 | 0.2224 | 0.2512 |
B3 animal | 0.9914 | 0.9975 | 0.9827 | 0.0087 | 0.0025 | 0.0175 |
D animal | 0.9713 | 0.9200 | 0.8835 | 0.0289 | 0.0805 | 0.1173 |
E animal | 0.9995 | 0.9999 | 0.9999 | 0.0005 | 0.0001 | 0.0001 |
*Distribution skewness was estimated using one-tailed Mann-Whitney's test.
p ≤ 0.005 is in bold, 0.005 <p ≤ 0.025 is in italics; Bonferonni's correction for simultaneous testing of two statistical hypotheses based on the same dataset: accessible surface area and atypical amino acid replacements positions.