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. 2011 May 29;41(5):776–779. doi: 10.1007/s10519-011-9475-0

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© The Author(s) 2011

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Fig. 1 — Distributions of the estimated QTL effect size before (blue) and after (red) adjustment in linear regression for association studies of QTL under two-tail extreme selection The case shown is when a quarter of the individuals were sampled at 1:1 ratio from the two tails of the trait distribution from a population of 5,000 individuals, each containing a QTL that had MAF of 10% and explained 5% of the trait variation. The means (SEs) of the estimated QTL effect size () from linear regression are, respectively, 0.144 (0.105) and 0.050 (0.036) before and after adjustment (Color figure online)

Inline graphic — Distributions of the estimated QTL effect size before (blue) and after (red) adjustment in linear regression for association studies of QTL under two-tail extreme selection The case shown is when a quarter of the individuals were sampled at 1:1 ratio from the two tails of the trait distribution from a population of 5,000 individuals, each containing a QTL that had MAF of 10% and explained 5% of the trait variation. The means (SEs) of the estimated QTL effect size () from linear regression are, respectively, 0.144 (0.105) and 0.050 (0.036) before and after adjustment (Color figure online)