Table 1.
Information and genotyping methods for OPRD1 and OPRK1 SNPs
| SNP ID (this study) | SNP ID (NCBI rs#) | Gene | Variation | Location | Amino acid | Chromosome position (bp) (NCBI Build 36.1) | Genotyping method |
|---|---|---|---|---|---|---|---|
| OPRD1^1 | rs569356 | OPRD1 | C/T | Upstream | Chr01: 29009273 | PCR-RFLP | |
| OPRD1^2 | rs1042114 | OPRD1 | G80T | Exon 1 | Cys27Phe | Chr01: 29011562 | PCR-RFLP |
| OPRD1^3 | rs678849 | OPRD1 | C/T | Intron 1 | Chr01: 29017775 | PCR-RFLP | |
| OPRD1^4 | rs2236857 | OPRD1 | A/G | Intron 1 | Chr01: 29034196 | TaqMan | |
| OPRD1^5 | rs2236855 | OPRD1 | G/T | Intron 1 | Chr01: 29034586 | TaqMan | |
| OPRD1^6 | rs2298896 | OPRD1 | A/C | Intron 1 | Chr01: 29038725 | TaqMan | |
| OPRD1^7 | rs421300 | OPRD1 | C/T | Intron 1 | Chr01: 29042180 | TaqMan | |
| OPRD1^8 | rs529520 | OPRD1 | G/T | Intron 1 | Chr01: 29047533 | TaqMan | |
| OPRD1^9 | rs12749204 | OPRD1 | A/G | Intron 1 | Chr01: 29048800 | TaqMan | |
| OPRD1^10 | rs2234918 | OPRD1 | C921T | Exon 3 | Gly307Gly | Chr01: 29062184 | PCR-RFLP |
| OPRD1^11 | rs204076 | OPRD1 | A/T | Downstream | Chr01: 29062977 | TaqMan | |
| OPRK1^1 | rs12675595 | OPRK1 | A/G | Upstream | Chr08: 54330478 | TaqMan | |
| OPRK1^2 | rs1051660 | OPRK1 | G36T | Exon 1 | Pro12Pro | Chr08: 54326115 | TaqMan |
| OPRK1^3 | rs6985606 | OPRK1 | C/T | Intron 1 | Chr08: 54323669 | TaqMan | |
| OPRK1^4 | rs997917 | OPRK1 | C/T | Intron 1 | Chr08: 54314931 | TaqMan | |
| OPRK1^5 | rs702764 | OPRK1 | C843T | Exon 3 | Ala281Ala | Chr08: 54304710 | TaqMan |
| OPRK1^6 | rs963549 | OPRK1 | C/T | Exon 3 (UTR) | Chr08: 54304377 | PCR-RFLP | |
| OPRK1^7 | rs7820807 | OPRK1 | C/T | Downstream | Chr08: 54301414 | TaqMan |
Abbreviations: RFLP, restriction fragment length polymorphism; SNP, single nucleotide polymorphism; UTR, untranslated region.