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. Author manuscript; available in PMC: 2011 Aug 28.
Published in final edited form as: Cell Signal. 2010 Jan 13;22(5):821–827. doi: 10.1016/j.cellsig.2010.01.006

Fig. 7.

Fig. 7

LRRK2-mediated induction of SNCA is repressed by the phospho-MEK1/2 inhibitor U0126. HEK293 cells transiently transfected with different LRRK2 constructs were treated with 10 μg/ml U0126 or vehicle (DMSO) for 12 h prior to harvesting. Total mRNA was extracted and SNCA-specific mRNA quantified by real-time RT-PCR to measure the induction levels of SNCA. Similar results were achieved in 3 independent experiments.