Table 4.
Management option | Advantage | Disadvantage | |
---|---|---|---|
Surveillance | - Excellent cancer cure rate - No treatment-related toxicity - Excellent salvage rate - Avoids overtreatment for most patients |
- Frequent follow-up CT, with associated long-term risks - Anxiety related to the risk of recurrence |
|
Radiation therapy | Dog-leg | - Excellent cancer cure rate - No need for routine CT - Lower recurrence rates compared with patients managed by surveillance |
- Most patients are overtreated - Second malignancy risk - Cardiotoxicity - Fertility impairment |
Para-aortic | - Excellent cancer cure rate - Lower recurrence rate than patients managed by surveillance |
- Frequent follow-up CT, with associated long-term risks - Second malignancy risk - Cardiotoxicity - Most patients are overtreated |
|
Chemotherapy | - Excellent cancer cure rate - Lower acute toxicity than radiation therapy |
- Long-term survival and toxicity unknown - Frequent follow-up CT, with associated long-term risks - Most patients are overtreated |
CT: computerised tomography