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. 2011 Aug 8;6:90. doi: 10.1186/1748-717X-6-90

Table 4.

Advantages and disadvantages of different management options in the treatment of stage I seminoma

Management option Advantage Disadvantage
Surveillance - Excellent cancer cure rate
- No treatment-related toxicity
- Excellent salvage rate
- Avoids overtreatment for most patients
- Frequent follow-up CT, with associated long-term risks
- Anxiety related to the risk of recurrence

Radiation therapy Dog-leg - Excellent cancer cure rate
- No need for routine CT
- Lower recurrence rates compared with patients managed by surveillance
- Most patients are overtreated
- Second malignancy risk
- Cardiotoxicity
- Fertility impairment

Para-aortic - Excellent cancer cure rate
- Lower recurrence rate than patients managed by surveillance
- Frequent follow-up CT, with associated long-term risks
- Second malignancy risk
- Cardiotoxicity
- Most patients are overtreated

Chemotherapy - Excellent cancer cure rate
- Lower acute toxicity than radiation therapy
- Long-term survival and toxicity unknown
- Frequent follow-up CT, with associated long-term risks
- Most patients are overtreated

CT: computerised tomography