Table 4.
Characteristics of patients that did and did not presented adverse drug reactions (ADRs)
| Characteristics | Patients ADR + | Patients ADR - | ||||
|---|---|---|---|---|---|---|
| Median | Mean | 95%CI(%) | Median | Mean | 95% CI(%) | |
| Age (years) | 47 | 49.1 | 42.0 - 56.3 | 52 | 51.1 | 47.3 - 55.0 |
| Treatment time (days) | 7.0 | 11.6 | 7.7 - 15.5 | 7.0 | 9.0 | 7.1 - 10.9 |
| Total Vancomycin dose (g) | 8.0 | 23.3 | 6.5 - 40.1 | 8.0 | 16.2 | 11.2 - 21.2 |
| Vancomycin Daily dose (g/day) | 1.4 | 2.0 | 1.1-2.8 | 1.0 | 1.9 | 1.5-2.4 |
| Initial creatinine (mg/dl) | 1.1 | 1.7 | 1.1 - 2.3 | 1.0 | 2.1 | 1.5 - 2.8 |
| Albumin (g/dl) | 1.4 | 1.9 | 1.6 - 2.1 | 1.75 | 1.9 | 1.6 - 2.1 |
Statistical analysis was performed using z-test. P > 0.05 for all the parameters evaluated comparing patients ADR + and -.