A. Luciferase expression from sequential CHAC1 promoter-reporter constructs is shown, as normalized to CMV-renilla, and co-transfected with plasmids expressing βGal, ATF4, ATF3 or sXBP1. B. Shown are luciferase expression results from CHAC1 promoter-reporter constructs containing a major CREB/ATF site and sequential internal deletions that were co -transfected with bGal, ATF4, ATF3 and sXBP1 expression plasmids.