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. Author manuscript; available in PMC: 2012 Aug 19.
Published in final edited form as: Circ Res. 2011 Jul 7;109(5):e27–e41. doi: 10.1161/CIRCRESAHA.111.241869

Figure 5. Regulation by HMOX1 in the Network.

Figure 5

A. Node border color signifies module membership and the fill indicates whether the Ox-PAPC treated expression level of a gene was correlated with HMOX1 basal levels (red is negative and green is positive correlation). siRNA-mediated knock-down of HMOX1 is shown for two siRNAs with the scrambled control in B. The fold changes of IL1b, IL6, MCP1, LDLR and INSIG1 were normalized to the fold changes measured in the scrambled control in C. mRNA was measured by RT-qPCR and averages ± s.d are shown. Asterisks indicate p-values less than 0.05.