Table 3.
Grade | Time of onset, location, severity and clinical impact of bleeding | Clinical condition | Diagnostic consequence | Therapeutic consequence | |
---|---|---|---|---|---|
A | Early, intra- or extraluminal, mild | Well | Observation, blood count, US and, if necessary, CT | No | |
B | Early, intra- or extraluminal, severe | Later, intra- or extraluminal, milda | Often well/intermediate, very rarely life-threatening | Observation, blood count, US, CT, angiography, endoscopyb | Transfusion of fluid-blood, intermediate care unit (or ICU), therapeutic endoscopy,b embolization, relaparotomy for early PPH |
C | Late, intra- or extraluminal, severe | Severely impaired, life-threatening | Angiography, CT, endoscopyb | Localization of bleeding, angiography and embolization, (endoscopyb) or relaparotomy, ICU |
Late, intra- or extraluminal, mild bleeding may not be immediately life-threatening to the patient but may be a warning sign of later severe haemorrhage (‘sentinel bleed’) and is therefore grade B.
Endoscopy should be performed when signs of intraluminal bleeding are present (melaena, haematemesis or blood loss via nasogastric tube).
US, ultrasonography; CT, computed tomography; ICU, intensive care unit; PPH, post-pancreatectomy haemorrhage.
Adopted from Wente et al.35