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. 2011 Aug;13(8):566–572. doi: 10.1111/j.1477-2574.2011.00336.x

Table 3.

International Study Group for Pancreatic Surgery grading of post-pancreatectomy haemorrhage after pancreatic surgery

Grade Time of onset, location, severity and clinical impact of bleeding Clinical condition Diagnostic consequence Therapeutic consequence
A Early, intra- or extraluminal, mild Well Observation, blood count, US and, if necessary, CT No

B Early, intra- or extraluminal, severe Later, intra- or extraluminal, milda Often well/intermediate, very rarely life-threatening Observation, blood count, US, CT, angiography, endoscopyb Transfusion of fluid-blood, intermediate care unit (or ICU), therapeutic endoscopy,b embolization, relaparotomy for early PPH

C Late, intra- or extraluminal, severe Severely impaired, life-threatening Angiography, CT, endoscopyb Localization of bleeding, angiography and embolization, (endoscopyb) or relaparotomy, ICU
a

Late, intra- or extraluminal, mild bleeding may not be immediately life-threatening to the patient but may be a warning sign of later severe haemorrhage (‘sentinel bleed’) and is therefore grade B.

b

Endoscopy should be performed when signs of intraluminal bleeding are present (melaena, haematemesis or blood loss via nasogastric tube).

US, ultrasonography; CT, computed tomography; ICU, intensive care unit; PPH, post-pancreatectomy haemorrhage.

Adopted from Wente et al.35