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. 2011 Feb 16;8(63):1400–1408. doi: 10.1098/rsif.2010.0669

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Figure 2. — TIRF adsorption measurements for three types of biomolecules show improved performance by nanogel coatings compared to covalently-coupled BSA coatings. The nanogel coating reduces adsorption of (a,b) the multi-labelled protein, Cy5-labelled streptavidin, (c,d) the singly labelled enzyme, mCherry-E. coli methionine aminopeptidase and (e,f) the singly labelled DNA, Cy5-labelled thrombin binding aptamer. (g) Molecule counts of biomolecule adsorption per unit area onto (black bars) covalently coupled BSA coatings and (grey bars) nanogel coatings. Error bars represent standard deviation of duplicate substrates.