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. Author manuscript; available in PMC: 2011 Aug 29.
Published in final edited form as: J Matern Fetal Neonatal Med. 2008 Oct;21(10):697–713. doi: 10.1080/14767050802053289

Figure 8.

Figure 8

SELDI-TOF MS ProteinChip immunoassays of amniotic fluid. (a) The IgG negative control for group 1 (preterm labor without infection/inflammation who deliver at term) (b) The IGFBP-1 capture antibody assay for the same amniotic fluid. (c) The IgG negative control for group 3 (preterm labor with intra-amniotic infection/inflammation). (d) The IGFBP-1 capture antibody assay for the same amniotic fluid (group 3). Peaks near 13 kDa correspond to proteolytic fragments of IGFBP-1, while the peak near 25 kDa correspond to the intact IGFBP-1 protein. Comparison of Figures (b) and (d) reveals evidence for proteolytic cleavage occurring in amniotic fluid from women with intra-amniotic infection/inflammation (group 3), but not in those without it (group 1).