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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Mol Nutr Food Res. 2011 May 2;55(6):905–920. doi: 10.1002/mnfr.201000648

Table 4.

Human intervention studies using green tea extracts in localized and advanced prostate cancer.

Location Type of Study Effect Daily Dose Reference
Green tea extract, Italy Intervention Study (n=60) 1 year Decreased progression from PIN to CaP 600 mg GTE (310.8 mg EGCG) Bettuzzi S et al. 2006 [33]
Green tea extract, Italy 1 year follow up Significantly lower rate of CaP No intervention Brausi M et al. 2008 [37]
Polyphenon E, US Intervention Study (n=25) Decreased serum PSA, HGF, VEGF 1300 mg Polyphenon E (800 mg EGCG) McLarty J et al. 2009 [34]
Green tea extract, Canada Intervention study (n=19) in hormone refractory CaP No effect 500 mg GTE (112.5 mg EGCG) Choan E et al. 2005 [35]
Green tea powder, USA Intervention study (n=42) in hormone refractory CaP PSA decreased by 50% in one out of 42 subjects, no effect, Grade 1 and 2 toxicity in 69% and no side effects in 31% of participants 6 g instant green tea powder in 6x 1g doses in hot water Jatoi A et al. 2003 [36]