Table 3.

Association between leptin levels and the risk of prediabetes in Chinese men and women aged 21–45 years.

Leptin tertiles	N		OR (95%CI)
(ng/ml)	NGT	PDM	Model A	Model B	Model C	Model D	Model E	Model F	Model G
Men
1st tertile(low)	67	29	1.0	1.0	1.0	1.0	1.0	1.0	1.0
2nd tertile	45	52	2.6(1.4–5.1)#	2.5(1.3–4.9)#	2.3(1.2–4.7)*	2.4(1.2–4.9)*	2.3(1.1–4.7)*	2.0(1.0–4.0)	1.7(0.9–3.4)
3rd tertile(high)	35	62	4.3(2.1–8.7)&	3.6(1.7–7.8)&	3.4(1.4–8.2)#	3.4(1.3–8.9)*	3.1(1.3–7.2)#	2.2(0.9–5.3)	2.0 (0.9–4.7)
P trend			<0.0001	0.0009	0.0056	0.0120	0.0073	0.0652	0.0878
Women
1st tertile(low)	57	37	1.0	1.0	1.0	1.0	1.0	1.0	1.0
2nd tertile	55	40	1.1(0.6–2.1)	1.1(0.6–2.1)	1.1(0.6–2.3)	1.3(0.6–2.6)	1.1(0.6–2.2)	1.1(0.6–2.1)	1.0(0.5–1.9)
3rd tertile(high)	35	60	3.1(1.5–6.2)#	3.1(1.5–6.3)#	3.2(1.4–7.3)#	3.8(1.6–9.3)#	2.9(1.4–6.3)#	3.0(1.3–6.8)#	1.9(0.9–4.0)
P trend			0.0014	0.0022	0.0056	0.0029	0.0048	0.0102	0.0993

^*p<0.05;

^#p<0.01;

^&p<0.001 compared with 1^st leptin tertile; NGT, normal glucose tolerance; PDM, prediabetes;

Model A, adjusted for age, education, occupation, active and passive smoking, alcohol consumption, and physical activity;

Model B, Model A plus triglyceride, cholesterol, high density lipoprotein-cholesterol, systolic blood pressure, diastolic blood pressure

Model C, Model B plus body mass index(BMI);

Model D, Model B plus percentage body fat;

Model E, Model B plus percentage trunk fat;

Model F, Model B plus waist circumference;

Model G, Model B plus homeostasis modeling accessible of insulin resistance(HOMA-IR).