Table 2. Oxylipin concentrations and immunostaining data from 1) Healthy controls 2) Healthy individuals following subway air exposure 3) Asthmatic controls and 4) Asthmatics following subway air exposure.

		Healthy (H)				Asthmatics (A)				p-valuesb
		Control (C)		Subway (S)		Control (C)		Subway (S)		Control	Subway	Healthy	Asthmatics
PUFA	Oxylipina (pM)	Average	CV(%)c	Average	CV(%)	Average	CV(%)	Average	CV(%)	H vs A	H vs A	C vs S	C vs S
AAd	5-HETE	199	52	170	44	306	107	240	84	0.2	0.2	0.3	0.4
	12-HETE	64	95	78	109	128	57	129	153	0.01	0.4	0.6	1.0
	15-HETE	672	129	666	83	1363	77	1089	99	0.04	0.2	1.0	0.3
	15-KETE	142	108	126	57	227	67	185	69	0.1	0.1	0.6	0.1
	LTB4	8	49	7	47	12	101	11	80	0.2	0.1	0.6	0.7
	6-trans-LTB4	47	55	39	56	44	92	38	86	0.8	0.9	0.2	0.5
	TXB2	64	43	60	42	66	54	63	67	0.9	0.8	0.5	0.7
	PGD2	15	96	15	68	32	108	39	148	0.1	0.1	0.9	0.6
	PGE2	10	48	13	87	15	50	11	89	0.04	0.7	0.4	0.1
	5(6)-EET	8	70	7	48	8	71	5	34	0.8	0.1	0.5	0.2
	8(9)-EET	7	72	4	58	7	46	6	59	0.7	0.1	0.04	0.3
LAe	9-HODE	202	103	423	138	188	49	128	44	0.8	0.05	0.04	0.02
	9-KODE	182	100	309	143	66	89	48	50	0.02	0.02	0.1	0.3
	13-HODE	1016	97	1458	111	1646	62	1151	85	0.1	0.5	0.2	0.1
	13-KODE	361	82	580	107	234	55	179	54	0.1	0.01	0.1	0.1
	EKODE	495	89	705	113	189	50	155	45	0.01	0.01	0.1	0.3
	9,10,13-TriHOME	262	58	312	81	193	66	116	47	0.2	0.005	0.4	0.1
	9,12,13-TriHOME	446	61	543	93	446	59	267	55	1.0	0.04	0.4	0.04
	9,10-DiHOME	408	38	448	44	310	51	267	77	0.1	0.01	0.3	0.3
	9(10)-EpOME	1877	28	1829	31	2012	48	2083	56	0.6	0.4	0.6	0.9
	12,13-DiHOME	476	41	517	50	373	53	322	75	0.1	0.03	0.3	0.3
	12(13)-EpOME	1938	27	1876	33	1976	44	2058	53	0.9	0.6	0.6	0.8
α-LAf	9-HOTE	9	129	20	161	11	48	9	55	0.5	0.2	0.1	0.1
	13-HOTE	52	100	72	116	91	62	71	100	0.04	1.0	0.2	0.3
EPAg	12-HEPE	9	101	13	67	16	99	11	108	0.1	0.6	0.1	0.4
	15-HEPE	64	132	68	74	125	89	93	84	0.1	0.3	0.9	0.2
DGLAh	15-HETrE	63	142	81	174	149	92	118	113	0.03	0.4	0.7	0.3
DHAi	17-HDoHE	278	137	301	95	461	72	379	93	0.2	0.5	0.9	0.4
ICCj	15-LOX-1	0.79	97	0.69	126	0.80	103	0.67	80	0.78	0.41	0.54	0.71
	COX-1	1.64	47	1.38	59	1.05	69	1.19	37	0.03	0.82	0.31	0.32
	COX-2	1.92	40	1.96	37	1.79	47	1.70	51	0.65	0.23	0.96	0.46
	PPARγ	0.55	43	0.73	89	0.60	54	0.55	63	0.93	0.29	0.80	0.41

^aOxylipin levels were normalized to the BAL-volume recoveries as described in Table S2 and Table S4,

^bp-values are based on unpaired for A vs H and paired Student's T-test for C vs S, respectively. Values of p<0.05 are italicized,

^cCoefficients of variation (%),

^dArachidonic acid,

^eLinoleic acid,

^fα-Linolenic acid,

^gEicosapentaenoic acid,

^hDihomo-γ-linolenic acid,

ⁱDocosahexaenoic acid,

^jImmunocytochemistry, RFU values normalized to DAPI intensities.