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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: J Pharm Sci. 2011 Mar 17;100(8):3396–3404. doi: 10.1002/jps.22527

Table 1.

IC50 of sterilized heparin measured by solution/surface competition SPR (based on duplicated experiments with less than 5% of errors)

IC50 (U/ml) to AT III IC50 (U/ml) to Human Thrombin
Non-Sterilized Heparin 2.0 2.3
30 min Sterilized Heparin 4.6 5.0
60 min Sterilized Heparin 6.8 5.5
120 min Sterilized Heparin >10 >10