Table 2. Homologous proteins of BTV (Culicoides borne), UMAV (mosquito borne) and GIV (tick-borne) orbiviruses.
| SegNo | Putative function | BTV genes | *UMAV genes | GIV genes |
| 1 | RNA dependent RNA Polymerase (Pol) | Seg-1, VP1(Pol) | Seg-1, VP1(Pol) | Seg-1, VP1(Pol) |
| 2 | Outer capsid protein (OCP1) | Seg-2, VP2(OCP1) | Seg-3, VP3(OCP1) | Seg-5, VP4(OCP1) |
| 3 | T2, Major subcore protein (T2) | Seg-3, VP3(T2) | Seg-2, VP2(T2) | Seg-2, VP2(T2) |
| 4 | Minor core protein - capping enzyme (Cap) | Seg-4, VP4(Cap) | Seg-5, VP4(Cap) | Seg-3, VP3(Cap) |
| 5 | Tubule protein (TuP) | Seg-5, NS1(TuP) | Seg-4, NS1(TuP) | Seg-4, NS1(TuP) |
| 6 | Outer capsid protein (OCP2) | Seg-6, VP5(OCP2) | Seg-6, VP5(OCP2) | Seg-6, VP5(OCP2) |
| 7 | Major core-surface protein (T13) | Seg-7, VP7(T13) | Seg-8, VP7(T13) | Seg-8, VP7(T13) |
| 8 | Viral inclusion body protein (ViP) | Seg-8, NS2(ViP) | Seg-7, NS2(ViP) | Seg-7, NS2(ViP) |
| 9 | Minor core protein- helicase enzyme (Hel) | Seg-9, VP6(Hel) | Seg-9, VP6(Hel) | Seg-9, VP6(Hel) |
| 10 | Virus release protein (VRP) | Seg-10, S3(VRP) | Seg-10, S3(VRP) | Seg-10, S3(VRP) |
*Variations in the segments are highlighted in bold italics.
The putative functions of UMAV proteins by comparison to the already established functions of BTV proteins. The functions and abbreviations used as per Mertens et al [2].