Table 1. Biological, molecular and cytogenetic features of CLL patients included in the study.

Variable	N° of positive/investigated patients (%)	Correlation with TTFT
ZAP-70	367/1011 (36.3%)	P<0.0001
CD38	306/1051 (29.1%)	P<0.0001
IGHV *	405/1126 (36%)	P<0.0001
No FISH alteration **	238/704 (33.8%)	P<0.0001
Del(13)(q14)	287/704 (40.7%)
Trisomy 12	98/704 (13.9%)
Del(11)(q23)	46/704 (6.5%)
Del(17)(p13)	35/704 (5%)

* the number of investigated sequences was 1131 (see text).

** FISH results according to the hierarchical classification [4]–[6].