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. 1999 Jan 1;13(1):76–86. doi: 10.1101/gad.13.1.76

Figure 1.

Figure 1

Schematic representation of the regions conserved between chicken and human Nrf2 proteins. (A) Six conserved domains, designated Neh1–Neh6, are found between human and chicken Nrf2. Neh1 corresponds to the CNC region and bZip structure. (B) Sequence homology in Neh2. Amino acid residues conserved between at least two proteins are shaded. The 33 amino-terminal residues, including the hydrophobic region, are conserved among Nrf1, hNrf2, and cNrf2 (ECH); the next 40 residues of Neh2 are rich in hydrophilic residues and specifically conserved between cross-species Nrf2 molecules. The strikingly homologous region, containing hydrophilic residues, is boxed. (▾) Restriction enzyme sites.