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. 2011 Sep 1;85(3):568–572. doi: 10.4269/ajtmh.2011.11-0194

Table 2.

Prevalence of pfmdr1 copy number in isolates collected from malaria patients with sensitive, re-infection, and recrudescence (before treatment and at the time of reappearance) responses, Thailand*

Pfmdr1 copy number Treatment outcome, no. (%)
Sensitive (n = 87) Failure (n = 30)
Re-infection (n = 9) Recrudescence
Pre-treatment (n = 21) Post-treatment (n = 18)
1 64 (73.6) 8 (88.9) 12 (57.1) 4 (22.2)
2 12 (13.8) 1 (11.1) 2 (9.5) 2 (11.1)
3 7 (8.0) 0 (0.0) 1 (4.8) 4 (22.2)
4 4 (4.6) 0 (0.0) 3 (14.3) 5 (27.8)
5 0 (0.0) 0 (0.0) 1 (4.8) 0 (0)
6 0 (0.0) 0 (0.0) 2 (9.5) 2 (11.1)
7 0 (0.0) 0 (0.0) 0 (0.0) 0 (0)
8 0 (0.0) 0 (0.0) 0 (0.0) 1 (5.6)
*

Pfmdr1 = P. falciparum multidrug resistance 1.

Statistically significant difference from pre-treatment recrudescence (P = 0.007).

Statistically significant difference between pre-treatment and post-treatment recrudescence (P = 0.007).