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p21−/− p57−m/+ double mutant mice display defects in skeletal muscle development. (A–H) H&E-stained transverse sections of E18.5 embryos. Arrows in A and B indicate intercostal skeletal muscles. (I,J) H&E-stained transverse sections of the chest region of E13.5 embryos. Arrows indicate various muscle groups. (fe) Femur; (ri) rib; (sk) skull; (sp) spinal cord. Scale bars, 200 μm.
