Figure 1. IRAK2-deficient pDCs are more resistant to the infection by MHV68.
Wild-type and IRAK2-deficient bone marrow-derived pDCs were infected with MHV68 (MOI=5) for 24 h. IFNα and IFNβ (A) TNFα and KC (B) concentrations in culture media were measured by ELISA. Results shown are the means and s. d. of triplicate determinations (* p< 0.05). (C) Cell lysates were analyzed by the Western method with antibodies against GFP, IRAK2 and actin.