Table 4.

Brain regions where age-related increase was observed in each group (voxel p = 0.005, cluster p = 0.01)

Area	Brain region	Age-related increase
		22q11DS					Normal control
		Coordinates			BA	Voxels (n)	Coordinates			BA	Voxels (n)
		X	Y	Z			X	Y	Z
Frontal	Ventrolateral prefrontal cortex
	Left	−18	19	−13	47	12
	Middle frontal gyrus
	Right						32	56	9	10	7
	Superior frontal gyrus
	Left	−4	11	48	6	11
Parietal	Precuneus
	Left						−18	−63	42	7	6
	Right	22	−70	42	7	17
	Inferior parietal lobule
	Left						−32	−44	37	40	14
	Superior parietal lobule
	Left						−29	−48	42	7	8
	Right						25	−63	48	7	10
	Angular gyrus
	Right						29	−59	37	39	5
Temporal	Fusiform gyrus
	Left						−47	−56	−18	37	7
	Inferior temporal gyrus
	Left						−51	−52	−13	20	24
Occipital	Inferior occipital gyrus
	Left						−36	−78	−7	19	28
	Middle occipital gyrus
	Left	−29	−81	−7	18	5	−40	−74	9	19	8
Limbic	Posterior cingulate gyrus
	Left						−25	−67	20	31	5

Minimum cluster size = 5 voxels