Table 5.

Brain regions where age-related decrease was observed in each group (voxel p = 0.005; cluster p = 0.01)

Area	Brain area	Age-related decrease
		22q11DS					Normal control
		Coordinates			BA	Voxels (n)	Coordinates			BA	Voxels (n)
		X	Y	Z			X	Y	Z
Frontal	Dorsolateral prefrontal cortex
	Left						−14	48	20	9	6
	Venrtolateral prefrontal cortex
	Left						−47	26	9	45	8
	Right						43	33	−7	47	9
	Middle frontal gyrus
	Left						−11	30	42	8	6
	Right						0	−19	48	6	27
							43	37	−13	11	5
	Precentral lobule
	Right						11	−30	53	6	18
Parietal	Precuneus
	Left	−14	−48	37	7	6
	Right	25	−37	26	31	11
	Inferior parietal lobule
	Right	47	−30	31	40	6
Temporal	Fusiform gyrus
	Right	32	−48	−13	37	19
	Middle temporal gyrus
	Right						36	0	−24	21	5
	Superior temporal gyrus
	Right	61	−30	20	42	8
Occipital	Fusiform gyrus
	Left	−18	−52	−13	19	5
	Right	36	−44	−7	37	14
Limbic	Cingulate gyrus
	Left	−4	7	31	24	10
	Right	18	−33	37	31	5	4	−33	42	31	25