Table 1.
Demographics, behavior scores, general, and regional morphometry
| Demographics | ICLP (n = 50) | Controls (n = 60) | P value for difference |
|---|---|---|---|
| Mean (SD), Median | Mean (SD), Median | ||
| Age (years) | 11.9 (3.3), 11.0 | 12.1 (2.7), 11.7 | 0.640 |
| Parental SES score | 2.67 (0.51), 3.0 | 2.33 (0.56), 2.0 | 0.001 |
| IQ and behavior scores | |||
| Full scale IQ (FSIQ) | 105.3 (13.3), 104 | 113 (16.6),110 | 0.010 |
| Hyperactivity/impulsivity/inattention (HII) | 12.7 (10.2), 9.3 | 8.9 (6.7), 7.0 | 0.021 |
| Brain measures | |||
| Intracranial volume (ICV) (cc) | 1,403 (148); 1,387 | 1,444 (111); 1,433 | 0.097 |
| Cortex volume (cc) | 746 (76), 740 | 758 (57), 758 | 0.368 |
| Cortex volume/ICV (%) | 53.3 (2.0), 53.1 | 52.5 (2.3), 52.4 | 0.083 |
| vmPFC/ICV (%) | 2.17 (0.18), 2.17 | 2.09 (0.13), 2.10 | 0.010 |
| Right vmPFC/ICV (%) | 1.08 (0.09), 1.08 | 1.03 (0.07), 1.04 | 0.008 |
| Left vmPFC/ICV (%) | 1.09 (0.10), 1.08 | 1.06 (0.07), 1.06 | 0.059 |
| Asymmetry coefficient (%) | −0.83 (3.4), −1.1 | −1.36 (4.1), −1.66 | 0.469 |