TABLE 3.

Univariate and Multivariate Analysis of Prior Pregnancy Losses After 20 Weeks' Gestation and Risk for Childhood CNS Tumors

	All Cases	LGG	HGG	MB	PNET	GCT	Ependymoma
No losses	1.0	1.0	1.0	1.0	1.0	1.0	1.0
Univariate
1 prior loss	0.72 (0.50–1.03)	0.49a (0.25–0.98)	1.08 (0.53–2.20)	Samples too small for analysis
≥2 prior losses	2.50a (1.13–5.51)	1.60 (0.50–5.10)	16.00a (1.79–143.15)
Multivariateb
1 prior loss	0.80 (0.55–1.16)	0.55 (0.27–1.12)	1.03 (0.50–2.11)	Samples too small for analysis
≥2 prior losses	3.13a (1.32–7.41)	2.96 (0.86–10.20)	14.28a (1.56–130.65)

Unadjusted and adjusted OR (95% CI).

^aP < .05.

^bAdjusted for birth weight, birth order, race, Hispanic ethnicity, and maternal age.