TABLE 4.

Univariate and Multivariate Analysis for Presence of Birth Defects and Risk of Childhood CNS Tumors

Presence of Birth Defect	All Cases	LGG	HGG	MB	PNET	GCT	Ependymoma
No	1.0	1.0	1.0	1.0	1.0	1.0	1.0
Yes
Univariate	2.00a (1.40–2.86)	0.85 (0.38–1.92)	1.11 (0.41–2.99)	3.00a (1.26–7.12)	3.64a (1.54–8.56)	6.40a (2.09–19.56)	1.00 (0.11–8.95)
Multivariateb	1.82a (1.25–2.65)	0.71 (0.29–1.72)	0.64 (0.19–2.24)	3.19a (1.29–7.87)	2.97a (1.21–7.28)	7.20a (2.10–24.63)	1.17 (0.13–10.61)

Unadjusted and adjusted OR (95% CI).

^aP < .05.

^bAdjusted for birth weight, birth order, race, Hispanic ethnicity, and maternal age.