Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of the experimentally observed product ratios involving reaction of propionaldehyde with N-PMP-protected α-imino ethyl glyoxylate with computed stereoselectivities based on transition state theory predictions involving N-PMP-protected α-imino methyl glyoxylate.
| Entry | Catalyst | Type | dr syn(1):anti(2) |
ee (%) syn (anti) |
|---|---|---|---|---|
| 1 | Proline | Exp. | 3:1 | >99 |
| 2 | Proline | Computed | 3.5:1 | 97 |
| 3 | Pipecolic acid | Exp. | 2:1 | >99 (>99) |
| 4 | Pipecolic acid | Computed | 1.4:1 | 93 (96) |
