Skip to main content
. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Recent Pat Inflamm Allergy Drug Discov. 2011 Jan;5(1):26–36. doi: 10.2174/187221311794474883

Table 1. Characteristic Symptoms and Treatment Options for Allergic Conjunctivitis.

Allergic Condition Cell Types Involved Clinical Symptoms Drugs for the Treatment
Seasonal Allergic Conjunctivitis (SAC) and Perennial Allergic Conjunctivitis (PAC) Eosinophil and mast cells are major inflammatory mediators Itching, redness, inflammation and tarsal papillae Antihistaminic, NSAIDs and mast cell stabilizers
Vernal Keratoconjunctivitis (VKC) Lymphocytes, eosinophil and mast cells Severe symptoms such as persistent itching, corneal ulceration and cobblestone papillae Immunomodulators, corticosteroids, NSAIDs, antihistaminic and mast cell stabilizers
Atopic Keratoconjunctivitis (AKC) Lymphocytes, basophils, eosinophil and mast cells Conjunctival damage, severe ocular itching and cataract Antihistaminic and mast cell stabilizers, NSAIDs.
In severe cases Immunomodulators and corticosteroids
Giant Papillary Conjunctivitis (GPC) Mast cells and lymphocytes Formation of giant papillae and mild ocular irritation due to contact lens Mast cell stabilizers, Antihistaminic and NSAIDs
Contact Dermatitis Lymphocytes and dendritic cells Erythema and mild ocular itching Antihistaminic, NSAIDs and mast cell stabilizers