Figure 6.

Live cell interferometer measures the mass of adherent cells: Frame shows several mouse fibroblast cells cultured directly on a polished silicon substrate. The color map indicates optical thickness measurements with blue being a low optical thickness relative to background and red being a high optical thickness. To the left are mass measurements of the four cells, as indicated, taken every 2 s for 200 min. The smaller optical thickness of the adherent cells versus nonadherent cells is easily measured by the LCI.