Table 3. Significantly regulated genes in PPD-stimulated PBMCs unique for tuberculosis infection and active disease with ratio >4.
GeneSymbol | Means | Ratio | Regulation | t-test | |
TB<BI/HC | TB<BI | HC | P value | ||
IL2 | 96.54 | 5.65 | 17.09 | up | 0.0005 |
CXCL9 | 10.39 | 1.32 | 7.86 | up | 0.0061 |
IFNG | 13.17 | 1.76 | 7.49 | up | 0.0006 |
CXCL10 | 4.67 | 0.77 | 6.05 | up | 0.0096 |
CXCL11 | 3.81 | 0.65 | 5.85 | up | 0.0400 |
CCL8 | 3.89 | 0.70 | 5.57 | up | 0.0199 |
BATF2 | 4.05 | 0.84 | 4.80 | up | 0.0029 |
TB/LTBI&HC | TB | LTBI&HC | P value | ||
BX090755 | 0.10 | 0.98 | 10.13 | down | 0.0050 |
IFNG | 24.46 | 3.53 | 6.93 | up | 0.0014 |
UBD | 8.01 | 1.38 | 5.81 | up | 0.0126 |
CXCL11 | 6.64 | 1.19 | 5.58 | up | 0.0474 |
CXCL9 | 16.42 | 2.95 | 5.57 | up | 0.0333 |
CXCL10 | 7.48 | 1.50 | 4.99 | up | 0.0267 |
RSPO3 | 1.76 | 0.36 | 4.85 | up | 0.0208 |
CCL8 | 6.22 | 1.30 | 4.77 | up | 0.0397 |
DB513559 | 0.09 | 0.37 | 4.38 | down | 0.0110 |
HMGA2 | 4.97 | 1.22 | 4.06 | up | 0.0001 |