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. 2011 Aug 31;6(8):e24338. doi: 10.1371/journal.pone.0024338

Figure 2. Integrin involvement in JNK2 activation by laminar shear stress.

Figure 2

(A) Integrin activation. BAECs plated on FN were sheared for the indicated times. then GST-FNIII9–11 binding assayed as described in Methods. Total cell lysates were immunoblotted for GST and tubulin. Values were normalized to total cell material using tubulin as a standard. Values are relative to unstimulated cells. (B) Blocking FN. Cells were sheared in the presence of anti-FN antibody 16G3 at 40 µg/ml, then lysed and processes as in A. Values are means ± SEM (n = 3). *p<0.05.