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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Stroke. 2011 Jul 7;42(9):2578–2583. doi: 10.1161/STROKEAHA.111.613182

Figure 3. PD-1 reduces the infiltration of inflammatory cells into the ischemic brain after MCAO.

Figure 3

Absolute numbers of CD3+ T cells (A), Gr1+ neutrophils (B), CD11b+CD45low microglia (C), and CD11b+CD45high macrophages (D) were significantly increased (**, P<0.001; ***, P<0.0001) in ipsilateral right (R) but not contralateral left (L) brain hemispheres of PD-1-KO versus WT mice after 60min MCAO and 96h reperfusion but not Sham-treatment. Values represent Mean ± SEM from five mice per group.