Table 2.

Comparison of Patients Randomly Assigned to MVAC (arm 1) and Control/Observation (arm 2) According to Baseline Characteristics

Characteristic	MVAC(arm 1)		Observation(arm 2)		Total
	No.	%	No.	%
Total patients	58	51	56	49	114
Sex
Female	7	12	9	16	16
Male	51	88	47	84	98
Age, years
< 65	37	64	41	73	78
≥ 65	21	36	15	27	36
Stage
pT1	21	36	16	29	37
pT2	37	64	40	71	77
Grade
1 or 2	2	3	1	2	3
3 or 4	56	97	55	98	111
No. of nodes identified
< 15	22	38	14	25	36
≥ 15	36	62	42	75	78
p21 status
Absent	24	41	22	39	46
Present	34	59	34	61	68
Lymphovascular invasion
No	33	57	25	45	58
Yes	13	22	14	25	27
Unknown	12	21	17	30	29
Bladder carcinoma in situ
No	16	27	12	21	28
Yes	34	59	32	57	66
Unknown	8	14	12	21	20

Abbreviation: MVAC, methotrexate, vinblastine, doxorubicin, and cisplatin.