Table 2.
Characteristic | MVAC(arm 1) |
Observation(arm 2) |
Total | ||
---|---|---|---|---|---|
No. | % | No. | % | ||
Total patients | 58 | 51 | 56 | 49 | 114 |
Sex | |||||
Female | 7 | 12 | 9 | 16 | 16 |
Male | 51 | 88 | 47 | 84 | 98 |
Age, years | |||||
< 65 | 37 | 64 | 41 | 73 | 78 |
≥ 65 | 21 | 36 | 15 | 27 | 36 |
Stage | |||||
pT1 | 21 | 36 | 16 | 29 | 37 |
pT2 | 37 | 64 | 40 | 71 | 77 |
Grade | |||||
1 or 2 | 2 | 3 | 1 | 2 | 3 |
3 or 4 | 56 | 97 | 55 | 98 | 111 |
No. of nodes identified | |||||
< 15 | 22 | 38 | 14 | 25 | 36 |
≥ 15 | 36 | 62 | 42 | 75 | 78 |
p21 status | |||||
Absent | 24 | 41 | 22 | 39 | 46 |
Present | 34 | 59 | 34 | 61 | 68 |
Lymphovascular invasion | |||||
No | 33 | 57 | 25 | 45 | 58 |
Yes | 13 | 22 | 14 | 25 | 27 |
Unknown | 12 | 21 | 17 | 30 | 29 |
Bladder carcinoma in situ | |||||
No | 16 | 27 | 12 | 21 | 28 |
Yes | 34 | 59 | 32 | 57 | 66 |
Unknown | 8 | 14 | 12 | 21 | 20 |
Abbreviation: MVAC, methotrexate, vinblastine, doxorubicin, and cisplatin.