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. Author manuscript; available in PMC: 2011 Nov 30.
Published in final edited form as: Biochemistry. 2010 Nov 3;49(47):10061–10071. doi: 10.1021/bi101229m

Figure 4.

Figure 4

Results of fitting activated two-state mechanism to M2 functional data. Inset, rimantadine-sensitive current-voltage relationships of Weybridge A/M2 (data from (12)) at pHin=7 pHout=5 (red triangles), pHin=6 pHout=8 (black squares), and pHin=8 pHout=6 (blue circles). Main panel, amantadine-sensitive current-pHout relationship of Udorn A/M2 at −20 mV. Rimantadine-insensitive leak currents have been subtracted for each measurement in the inset; amantadine-insensitive leak currents have been subtracted for each measurement in the main panel.