Table 1.
1 Comparison of the IgE anti-Dsg1 Autoantibodies in FS and Control Groups
Comparison | Difference Between Means of Index Value | Simultaneous 95% Confidence Limits | p Values | |
---|---|---|---|---|
FS vs PF USA/Japan2 | 0.69 | 0.42 | 0.96 | 0.05 |
FS vs HC Endemic area-Brazil2 | 0.90 | 0.73 | 1.07 | 0.05 |
FS vs HC Non-Endemic area-Brazil | 1.01 | 0.78 | 1.25 | 0.05 |
FS vs HC USA/Japan | 1.32 | 1.13 | 1.51 | 0.05 |
PF USA/Japan vs HC USA/Japan | 0.63 | 0.35 | 0.91 | 0.05 |
HC Endemic area-Brazil vs HC Non-endemic area-Brazil | 0.12 | −0.11 | 0.34 | ns2 |
HC USA/Japan vs HC Endemic area-Brazil | −0.42 | −0.61 | −0.23 | 0.05 |
HC USA/Japan vs HC Non-endemic area -Brazil | −0.31 | −0.55 | −0.06 | 0.05 |
Analysis of differences between groups used one-way analysis of variance with adjustment for multiple comparisons by Tukey’s studentized range test. Analysis was done on log(IgE+40) and log(IgG4+2) as these transformed variables were approximately normally distributed. Analysis was done in the R 2.9 software (Team, 2009).
FS = Fogo Selvagem, PF = Pemphigus foliaceus, HC = Healthy controls, ns = Non significant comparison