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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Immunity. 2011 May 19;34(5):807–819. doi: 10.1016/j.immuni.2011.03.022

Figure 7. Antigen-specific T cells show limited effector function but high effector potential in Mtb-induced granulomas.

Figure 7

(A) Animals were treated as in Figure 4 except they were infected with Mtb. Representative histograms gated on CD4+EGFP+ cells from p25-EGFP-bearing infected animals that had been injected with PBS or Ag85b peptide 2 hours prior to analysis. (B) IHLs were restimulated with P+I prior to analysis in order to detect maximum cytokine production. (C) Quantification of percentage of p25 T cells expressing IFN-γ. Graph shows mean+/− SD from at least three mice per group and is representative of two similar experiments. P values from a two-tailed T test are shown.