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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Org Lett. 2010 Jan 15;12(2):336–339. doi: 10.1021/ol902681t

Scheme 4.

Scheme 4

Propargylations and dipolar cycloadditions with substituted silyl ethers

a All yields refer to isolated products after purification over silica gel. b All diastereomeric ratios were determined by 1H NMR analysis on crude material.

c The (Sa) enantiomer of the allenylsilane 1 was used for the propargylation reaction. dCycloaddition reaction run in chlorobenzene at 150 ºC.