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Pharmacological inhibition of IKBKB in NSCLC cells. Alamar Blue cell viability assays were performed to measure the effect of IKBKB inhibition by a cell permeable, competitive ATP inhibitor, IKK-2 inhibitor IV on 5 NSCLC cell lines. H2122, H23, H3255, and HCC95 harboured genetic alterations to either IKBKB and/or one or more of the KEAP1 E3-ligase complex components while H1650 was not altered at the DNA level.
