. 2011 Sep;80(3):426–433. doi: 10.1124/mol.111.072504

TABLE 1.

Sequence alignment

Bold and underlined characters indicate experimentally determined residues that, when mutated, affect action of BTG 502 and deltamethrin, respectively. Position of a residue is designated by a symbol that identifies a segment and a relative position of the residue in the segment.

Channel	Domain	First Residue
			`o1`	`o11`	`o21`
KcsA	M1	23	`LHWRAAGAAT`	`VLLVIVLLAG`	`SYLAVLAER`
K_v1.2	S5	323	`ASMRELGLLI`	`FFLFIGVILF`	`SSAVYFAEA`
BgNa_v1-1	IS5	265	`ESVKNLRDVI`	`ILTMFSLSVF`	`ALMGLQIYM`
	IIS5	902	`RTVGALGNLT`	`FVLCIIIFIF`	`AVMGMQLFG`
	IIIS5	1397	`QAIPSIFNVL`	`LVCLIFWLIF`	`AIMGVQLFA`
	IVS5	1715	`MSLPALFNIC`	`LLLFLVMFIF`	`AIFGMSFFM`
			`p33`	`p41`	`p51`
KcsA	P	59	`LITYPRAL`	`WWSVETATTV`	`GYGDLYPV`
K_v1.2	P	358	`FPSIPDAF`	`WWAVVSMTTV`	`GYGDMVPT`
BgNa_v1-1	IP	300	`CIKNFWAF`	`LSAFRLMTQD`	`YWENLYQL`
	IIP	937	`VERFPHSF`	`MIVFRVLCGE`	`WIESMWDC`
	IIIP	1436	`STTLSKAY`	`LCLFQVATFK`	`GWIQIMND`
	IVP	1750	`GLDDVQSM`	`ILLFQMSTSA`	`GWDGVLDG`
			`i1`	`i11`	`i21`	`i31`
KcsA	M2	86	`LWGRLVAVVV`	`MVAGITSFGL`	`VTAALATWFV`	`GREQERR`
K_v1.2	S6	385	`IGGKIVGSLC`	`AIAGVLTIAL`	`PVPVIVSNFN`	`YFYHRET`
BgNa_v1-1	IS6	402	`PWHMLFFIVI`	`IFLGSFYLVN`	`LILAIVAMSY`	`DELQKKA`
	IIS6	981	`WSCIPFFLAT`	`VVIGNLVVLN`	`LFLALLLSNF`	`GSSNLSA`
	IIIS6	1506	`IYMYLYFVFF`	`IIFGSFFTLN`	`LFIGVIIDNF`	`NEQKKKA`
	IVS6	1806	`TVGLAFLLSY`	`LVISFLIVIN`	`MYIAVILENY`	`SQATEDV`

o, outer helix; p, P-loop; i, inner helix.