# Patients Randomized |
Study Groups |
Stratification | Significance Demonstrated |
% Change Identified in Trial |
---|---|---|---|---|
312 | Sunitinib n = 207 Placebo n = 105 |
Based on prior outcome on imatinib treatment: progression within 6 months vs progression beyond 6 months or intolerance to imatinib | Improvement in progression-free survival | Hazard ratio 0.33 (95% CI 0.23–0.47, p < 0.0001) |