Fig. 9.

Mice underwent filament perforation of the right anterior cerebral artery resulting in subarachnoid hemorrhage. Mice received intraperitoneal vehicle or MnTnHex-2-PyP over a 72-h recovery period. A, neurologic function was then assessed. Circles indicate individual animal values. Horizontal lines indicate group median values. 0 = no neurologic deficit. B to D, mice then underwent in situ vascular casting and measurement of diameters of the ipsilateral ICA (B), MCA (C), and ACA (D). Sham-operated mice provide normal reference values. Circles indicate individual animal values. Horizontal bars indicate group mean values.