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. 2011 Sep;338(3):906–916. doi: 10.1124/jpet.110.176701

TABLE 2.

Physiologic values for 90-min MCAO, treatment onset 5 min after reperfusion onset

All values are mean ± S.D.

Vehicle MnTnHex-2-PyP
n 17 18
Preischemia body weight, g 255 ± 14 262 ± 14
Body weight 7 days after ischemia, g 239 ± 51 275 ± 32*
Body weight change, g −17 ± 47 +14 ± 27*
10 min preischemia, g
    MAP, mm Hg 81 ± 10 83 ± 7
    Arterial pH 7.44 ± 0.04 7.43 ± 0.04
    PaCO2, mm Hg 38 ± 4 35 ± 3*
    PaO2, mm Hg 163 ± 27 156 ± 23
    Blood glucose, mg/dl 75 ± 11 72 ± 8
    Hematocrit, % 42 ± 2 41 ± 2*
    Pericranial temperature, °C 37.5 ± 0.1 37.5 ± 0.1
45 min after ischemia onset
    MAP, mm Hg 76 ± 13 75 ± 10
    Arterial pH 7.41 ± 0.05 7.41 ± 0.07
    PaCO2, mm Hg 39 ± 6 38 ± 5
    PaO2, mm Hg 167 ± 13 160 ± 17
    Pericranial temperature, °C 37.5 ± 0.1 37.5 ± 0.1
10 min after ischemia
    MAP, mm Hg 73 ± 6 72 ± 7
    Arterial pH 7.39 ± 0.06 7.38 ± 0.07
    PaCO2, mm Hg 40 ± 5 39 ± 6
    PaO2, mm Hg 173 ± 13 171 ± 15
    Pericranial temperature, °C 37.5 ± 0.1 37.5 ± 0.1
*

P < 0.05.

HHS Vulnerability Disclosure